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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC1H1 All Species: 25.45
Human Site: S3965 Identified Species: 46.67
UniProt: Q14204 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14204 NP_001367.2 4646 532408 S3965 G I W L D S S S P E Q T V P Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112455 4147 474593 R3561 G V K A N M L R T F S S I P V
Dog Lupus familis XP_537556 4646 532374 S3965 G I W L D S S S P E Q T V P Y
Cat Felis silvestris
Mouse Mus musculus Q9JHU4 4644 532007 S3963 G I W L D S S S P E Q T V P Y
Rat Rattus norvegicus P38650 4644 532233 S3963 G I W L E S S S P E Q T V P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512683 4644 532495 S3963 C I W L D S S S P E Q T V P Y
Chicken Gallus gallus XP_421371 4617 529846 A3974 F R P D R L L A M A H T F V S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036210 4643 533172 S3964 F M W L E S N S P E L S V P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37276 4639 530166 S3949 G A W L Q Q S S P E Q V V P Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19020 4568 521560 N3913 T S W L T N D N P E S N V P V
Sea Urchin Strong. purpuratus XP_797645 4652 531803 N3962 T K W L N S Q N P E H S V P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36022 4092 471329 I3507 D P S G D I P I F L R S R V R
Red Bread Mold Neurospora crassa P45443 4367 495560 T3781 D D D H V I E T L E T L K T E
Conservation
Percent
Protein Identity: 100 N.A. 83.9 99.2 N.A. 99 98.5 N.A. 98.4 95.5 N.A. 90.9 N.A. 71.9 N.A. 55.6 74.5
Protein Similarity: 100 N.A. 84.5 99.6 N.A. 99.4 99.2 N.A. 99.4 97.1 N.A. 95.8 N.A. 85.2 N.A. 73.3 86.2
P-Site Identity: 100 N.A. 13.3 100 N.A. 100 93.3 N.A. 93.3 6.6 N.A. 60 N.A. 66.6 N.A. 40 46.6
P-Site Similarity: 100 N.A. 40 100 N.A. 100 100 N.A. 93.3 13.3 N.A. 86.6 N.A. 66.6 N.A. 53.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.8 49.8
Protein Similarity: N.A. N.A. N.A. N.A. 48.9 67.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 8 0 8 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 8 8 39 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 16 0 8 0 0 77 0 0 0 0 8 % E
% Phe: 16 0 0 0 0 0 0 0 8 8 0 0 8 0 0 % F
% Gly: 47 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 16 0 0 0 0 % H
% Ile: 0 39 0 0 0 16 0 8 0 0 0 0 8 0 0 % I
% Lys: 0 8 8 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 70 0 8 16 0 8 8 8 8 0 0 0 % L
% Met: 0 8 0 0 0 8 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 16 8 8 16 0 0 0 8 0 0 0 % N
% Pro: 0 8 8 0 0 0 8 0 70 0 0 0 0 77 0 % P
% Gln: 0 0 0 0 8 8 8 0 0 0 47 0 0 0 16 % Q
% Arg: 0 8 0 0 8 0 0 8 0 0 8 0 8 0 8 % R
% Ser: 0 8 8 0 0 54 47 54 0 0 16 31 0 0 8 % S
% Thr: 16 0 0 0 8 0 0 8 8 0 8 47 0 8 0 % T
% Val: 0 8 0 0 8 0 0 0 0 0 0 8 70 16 16 % V
% Trp: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _